Spectral Karyotyping and Comparative Genomic Hybridization Data
نویسندگان
چکیده
Spectral Karyotyping (SKY) (1–7) and Comparative Genomic Hybidization (CGH) (8– 11) are complementary fluorescent molecular cytogenetic techniques that have revolutionized the detection of chromosomal abnormalities. SKY permits the simultaneous visualization of all human or mouse chromosomes in a different color, facilitating the detection of chromosomal translocations and rearrangements (Figure 1). CGH uses the hybridization of differentially labeled tumor and reference DNA to generate a map of DNA copy number changes in tumor genomes.
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تاریخ انتشار 2016